| INVITED REVIEW |
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| Year : 2008 | Volume
: 3
| Issue : 1 | Page : 55-64 |
Surgical pathology of pediatric epilepsy
Vani Santosh, TC Yasha
Department of Neuropathology, NIMHANS, Bangalore, India
Correspondence Address:
Vani Santosh
Department of Neuropathology, NIMHANS, Bangalore
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1817-1745.40591
The underlying pathological substrates of localization-related epilepsy are varied. In children, the foremost among these are the malformative disorders of cortical development of which focal cortical dysplasia (FCD) is the most prominent. Other conditions include tuberous sclerosis, Sturge-Weber syndrome, vascular malformations, ischemic lesions and epilepsy-associated tumors. As in adults, medial temporal sclerosis is also a common histopathological finding. Resective surgery for extratemporal lesions is now the treatment of choice as more accurate identification of lesion with modern imaging and electrophysiological techniques is possible and a good surgical outcome is seen in most cases. This review describes the common causal histopathological substrates of epilepsy in children.
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