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Year : 2016  |  Volume : 11  |  Issue : 4  |  Page : 305-308

Infantile tremor syndrome: Role of Vitamin B12 revisited

1 Department of Pediatrics, Chirayu Medical College, Bhopal, Madhya Pradesh, India
2 Department of Pediatrics, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India
3 Department of Biochemistry, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India
4 Department of Pathology, Chandulal Chandrakar Memorial Medical College, Durg, Chhattisgarh, India
5 Department of Pediatrics, R. D. Gardi Medical College, Ujjain, Madhya Pradesh, India; Department of Public Health Sciences, Global Health (IHCAR), Karolinska Institutet, Stockholm, Sweden

Correspondence Address:
Rajesh Gupta
Department of Pediatrics, IInd Floor, Chirayu Medical College and Hospital, Bhopal - 462 030, Madhya Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1817-1745.199463

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Objective: To study the role of Vitamin B12 as an etiological factor in patients of infantile tremor syndrome (ITS). Methods: Twelve consecutive admissions of children diagnosed clinically as ITS were assessed. Assessment was done using a predefined pro forma to document patient demographic factors, general examination, systemic examination as well as relevant hematological and biochemical investigations. Results: Out of the 12 cases of ITS, 6 were males and 6 were females. Two cases had serum B12 levels below reference values, five had levels in low normal range, and remaining five had normal values. Conclusions: Role of Vitamin B12 deficiency as an etiological factor in the patients of ITS is inconclusive.


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