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Year : 2021  |  Volume : 16  |  Issue : 2  |  Page : 91-96

Electrical status epilepticus during slow-wave sleep (ESES): Current perspectives

1 Department of Pediatric Neurology, Kahramanmaraş Necip Fazil Hospital, Kahramanmaraş, Turkey
2 Department of Pediatric Neurology, Izmir Katip Celebi University, Izmir, Turkey
3 Department of Pediatric Neurology, Ege University, Izmır, Turkey

Correspondence Address:
Dr. Pinar Gencpinar
Department of Pediatric Neurology, Izmir Katip Celebi University, Izmir, Turkey, Cıglı 35620, Izmir.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpn.JPN_137_20

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Electrical status epilepticus during slow-wave sleep (ESES) is an epilepsy syndrome with sleep-induced epileptic discharges and acquired impairment of cognition or behavior. Since the disease’s original description in 1971, no clear consensus has emerged on diagnostic criteria or optimal treatment. The treatment of ESES can be challenging, often including numerous antiepileptic drugs, immunomodulatory agents, and even surgical interventions. There is little evidence to guide treatment because only retrospective studies and case reports on the efficacy of treatment of ESES are present in literature. In this paper, we aim to analyze the etiopathogenesis of ESES in the new genetic era and to evaluate the treatment modalities in accordance with the genetic data and electroclinic spectrum of ESES.


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