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Year : 2021  |  Volume : 16  |  Issue : 4  |  Page : 338-340

Childhood pineal glioblastoma: Case report

1 Department of Neurosurgery, School of Medicine, Erciyes University, Kayseri, Turkey
2 Department of Pediatrics, Division of Pediatric Neurology, Faculty of Medicine, Gaziantep University, Şahinbey, Gaziantep, Turkey
3 Department of Radiology, Medicalpark Hospital, Gaziantep, Turkey
4 Department of Pathology, Gaziantep Patomer, Gaziantep, Turkey
5 Department of Neurosurgery, Medicalpark Hospital, Gaziantep, Turkey

Correspondence Address:
Dr. Tugay Atalay
Department of Neurosurgery, School of Medicine, Erciyes University, Kayseri
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpn.JPN_232_20

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Pineal glioblastomas (GBMs) are extremely rare tumors. Herein we will present a pediatric patient with GBM located in pineal region who was admitted with the symptoms of increased intracranial pressure and treated with surgical resection and radiotherapy. Introduction: Pineal region tumors are extremely rare accounting for less than 1% of all brain tumors. The most common type of pineal region tumors is germ cell tumor, followed by pineal parenchymal tumors, gliomas, atypical tumors, and the others. Case Report: A 5-year-old girl was admitted with complaints of headache, dizziness, imbalance in walking, and impaired vision for 1 month. Her neurological examination revealed a tendency to sleep, anisocoric pupillae, mesh eye pupil, dilated lateral gaze paralysis, and left hemiparasia (4/5 muscle strength). In magnetic resonance imaging, a mass was observed in the pineal region that infiltrates the right thalamus and right superior peduncle, isointense and hyperintense in T1 sections, hyperintense in T2 sections, having centrally contrasted areas in post-contrast sections. Due to the presence of evident hydrocephalus, a ventricular shunt was inserted and then through supracerebellar to infratentorial approach the lesion was removed subtotally. The histopathological diagnosis was GBM. GBMs in the pineal region are extremely rare tumors carrying poor prognosis. The patients are generally presented with the signs and symptoms of increased intracranial pressure. GBMs should be kept in mind in differential diagnosis of tumors in the pineal region.


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