home : about us : ahead of print : current issue : archives search instructions : subscriptionLogin 
Users online: 4800      Small font sizeDefault font sizeIncrease font size Print this page Email this page
 CASE REPORT
Year : 2021  |  Volume : 16  |  Issue : 4  |  Page : 344-346

Herpes simplex virus-2 encephalitis complicated with multiple cranial neuritis and dysautonomia


Department of Paediatrics, University of Colombo Colombo 7, Colombo, Sri Lanka

Correspondence Address:
Prof. Jithangi Wanigasinghe
Department of Paediatrics, University of Colombo Colombo 7
Sri Lanka
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpn.JPN_239_20

Rights and Permissions

Introduction: Herpes simplex encephalitis (HSE) is mainly caused by herpes simplex virus-1 infection (HSV-1). Herpes simplex virus-2 (HSV-2) infection is rare except in neonates or the immune-compromised. Cranial neuritis is rarely reported in association with HSE. This case study in an eleven-month-old followed by a literature review on cranial neuritis in HSE in children is presented due to the rarity of both situations. Case Report: An eleven-month old otherwise healthy infant presented with encephalitis due to HSV-2 infection which was complicated with dysautonomia manifesting as blood pressure fluctuations and tachycardia, and cranial neuritis manifesting as unilateral ptosis and palatal palsy. The clinical presentation of brain stem encephalitis was confirmed by the Magnetic Resonance Imaging findings of hyperintense foci and contrast enhancement in the medulla oblongata. Following treatment with acyclovir, he made a complete recovery. He did not have any clinical or laboratorial evidence suggestive of immune deficiency. Conclusion: HSV-2 infection can occur beyond the neonatal age group even in the absence of immune compromise. The brainstem encephalitis manifesting as cranial neuritis and autonomic dysfunction made a complete recovery.






[FULL TEXT] [PDF]*


        
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1508    
    Printed125    
    Emailed0    
    PDF Downloaded36    
    Comments [Add]    

Recommend this journal